From the February 9, 2021, edition of Fox News' Tucker Carlson Tonight

TUCKER CARLSON (HOST): So, we spend a lot of time talking about the trans question. We’re lectured a lot about it. I think most people, including me, have very little idea of what it means, medically. You said this is a long-term commitment between the patient and the health care provider. What do you mean by that, exactly?

ABIGAIL SHRIER (ANTI-TRANS AUTHOR): Well, to maintain the effects of something like testosterone, you need to stay on it, otherwise you will end up in this in-between looking state. For a woman to maintain the effects, the secondary characteristics of a man, she needs to stay on massive, massive doses. Now, that doesn't mean that some of the effects aren't permanent, many of them are, but she still has to maintain that appearance, and she has to keep coming in for checkups to look at her blood levels. Now, that said, very often these teenagers who come in at 18 and, yes, far below 18 depending on the state, to a Planned Parenthood clinic, very often they never see a doctor.

CARLSON: I mean, I think we know that there are long-term health effects of flooding your body with hormones that you don't naturally produce. Do we know what the long-term effects of this might be?

SHRIER: Well, some of them include infertility, vaginal and uterine atrophy, risk of cardiac events, and of course, the great unknown, which is that we've never done this the biological women for decades, and that's what we're doing now so we really don't know all of the long-term effects.